EBMPAC Evidence // Clinical signal
Show me the data.Then show me what it changes.
Concise, clinically relevant airway reviews for clinicians who want more than an abstract—and less than another opinion disguised as evidence.
Original study · Independent review · PAC interpretation · Practice context
01 // From paper to practice
Evidence is only useful when it changes the next decision.
Each review starts with the original study, adds independent commentary, and separates the headline result from the clinical judgment required to use it.
Read the signal. Examine the context. Keep the uncertainty visible.Swipe through the reading method →
Find the signal
Start with the question, population, intervention, comparator, and patient-centered outcome.
Interrogate the edges
Look for exclusions, protocol details, uncertainty, and the places where the study cannot answer for you.
Translate deliberately
Decide what changes at the bedside—and what still depends on physiology, judgment, and rehearsal.
02 // Evidence desk
Three studies. Three decisions worth revisiting.
Every dossier preserves the full source chain: original publication, expert commentary, PAC interpretation, and the visual carousel.
No mortality advantage
28.1% / 29.1%28-day mortality · ketamine / etomidate2,365 critically ill adultsNew England Journal of Medicine · RSI Trial · 2025
Ketamine or etomidate for tracheal intubation?
Ketamine did not reduce 28-day in-hospital mortality compared with etomidate. Cardiovascular collapse during intubation occurred more often in the ketamine group.
The result challenges a reflexive “ketamine is safer” narrative. Drug choice still belongs inside a complete hemodynamic plan that accounts for dose, physiology, resuscitation, and local practice.
Open the PAC visual carousel+
Make failure visible sooner
DAS 25Recognition · declaration · progressionAdult unanticipated difficult intubationBritish Journal of Anaesthesia · DAS 2025
The 2025 DAS airway guidelines
The updated pathway emphasizes earlier recognition of failure, clearer thresholds for declaring CICO, fewer attempts, faster progression, and surgical FONA as a time-critical rescue.
An algorithm becomes useful through rehearsal. Teams still need shared language, role clarity, equipment readiness, and deliberate practice before the pathway is needed.
Open the PAC visual carousel+
Hypoxemia cut by half
9.1% / 18.5%SpO₂ <85% · NIV / oxygen mask1,301 critically ill adultsNew England Journal of Medicine · PREOXI Trial · 2024
Noninvasive ventilation for preoxygenation
Preoxygenation with noninvasive ventilation lowered the incidence of hypoxemia during emergency intubation compared with an oxygen mask.
The trial supports NIV for many critically ill adults, but it does not resolve every airway. Setup time, aspiration risk, patient tolerance, the underlying physiology, and immediate urgency still matter.
Open the PAC visual carousel+
03 // Keep the signal moving
Explore the evidence. Interpret it intelligently.
Follow PAC for new visual reviews, practice-changing trials, airway guidelines, and the clinical conversations that follow.
You must be logged in to post a comment.